Idyllically set on the banks of the St. Lawrence River in Clayton, NY, 1000 Islands Harbor Hotel welcomes guests with luxury accommodations and unmatched hospitality. Conveniently located in the quaint village of Clayton, home to the Antique Boat Museum and Clayton Opera House, and nearby Boldt Castle, our hotel provides the perfect vantage point from which to explore it all. Discover wine trails, craft breweries, distilleries, lighthouses, castles, historic attractions, unparalleled recreation, and more. The AAA Four Diamond property is designed to delight year-round, offering 105 spacious deluxe guestrooms and suites, an array of thoughtful touches, and exemplary service to enhance your stay. Guests enjoy upscale dining and cocktails at Seaway Grille and 1000 Islands Bar, offering local wines and craft beer. Boasting an elegant ballroom and spacious lawn for tented events, the hotel has become a sought-after venue for destination weddings, meetings, and corporate events. The 1000 Islands Harbor Hotel is part of the Harbor Hotel Collection, a portfolio of AAA Four Diamond Caliber properties that offer upscale accommodations and extraordinary service in unique waterfront destinations.